Waxaan dooneynaa inaan nafteena u hurno inaan siino iibsadayaashayada sharafta leh oo ay la socdaan alaabada iyo adeegyada aadka ugu xamaasadsan ee Naqshadaynta Fashion-ka cusub ee Shiinaha Tayada SareKallikreinCAS 9001-01-8 Kininogenase xameetidaKallikreinBudada, Marna ma joojinay hagaajinta farsamadayada iyo tayadayada si aan ula socono isbeddelka horumarinta warshadahan oo aan si fiican u daboolno qanacsanaantaada.Haddii aad xiisaynayso alaabtayada, fadlan nala soo xiriir si xor ah.
Waxaan dooneynaa inaan nafteena u hurno inaan siino iibsadayaashayada sharafta leh si wadajir ah alaabada iyo adeegyada ugu xiisaha badan ee loogu talagalayShiinaha Kininogenase Kallikrein, Kallikrein, Waayo-aragnimadeena waxay naga dhigaysaa mid muhiim u ah indhaha macaamiishayada.Tayadayadu waxay lafteeda u hadashaa guryaha sida inayan isku dhejin, daadin ama jabin, sidaa darteed macaamiishayadu waxay had iyo jeer ku kalsoonaan doonaan markay dalbanayaan dalabka.
1. Characters: Caddaan ama ku dhawaad budo cad, oo aan ur lahayn.
2. Isha Soosaarka: Beeryarada Porcine.
3. Habka: Kallidinogenase waxaa laga soo saaraa beeryarada doofaarka ee caafimaadka leh.
4. Tilmaamaha iyo isticmaalka: Alaabtan waxaa loo isticmaali karaa noocyo kala duwan oo ah cudurrada wadnaha iyo xididdada dhiigga, sida cudurada wadnaha, arteriosclerosis maskaxda, thrombosis cerebral thrombosis, cilladaha sahayda dhiigga retinal iyo cudurrada xididdada durugsan.Saameyn daweyn oo wanaagsan ku yeelata cilmi-baarisyadii ugu dambeeyay ee ka hortagga hore ee microangiopathy macaanka iyo nephropathy macaanka, waxay yareyn kartaa soosaarka albumin-ka.Xogta caafimaad ee gudaha iyo dibaddaba waxay soo jeedinaysaa in ay kordhin karto dhaqdhaqaaqa shahwada iyo tirada wax-soo-saarka, oo ay leedahay saamayn dawo ah oo lagu daweynayo qaar ka mid ah madhalaysnimada ragga.
Waxa lagu soo saaray aqoon-is-weydaarsiga GMP
· 27 sano oo enzyme noole R&D taariikhda
Walxaha ceeriin waa la raadin karaa
U hoggaansamaan heerka macaamiisha
Dhoofinta in ka badan 30 waddan iyo gobollo
Inuu leeyahay awoodda maaraynta nidaamka tayada sida US FDA, Japan PMDA, South Korea MFDS, iwm.
Walxaha Tijaabada | Tilmaamaha Shirkadda | ||
CP | JP | ||
Jilayaasha | Caddaan ama ku dhawaad cad cad, oo aan ur lahayn | Caddaan ilaa budo yar oo bunni ah, aan ur lahayn ama ay daciif tahay | |
Aqoonsiga | R (Heerka Hydrolysis): 0.12~0.17 | R (Heerka Hydrolysis): 0.12~0.16 | |
Chromatography dareere: Waafaqsan | I: ≤ 0.2 | ||
Tijaabooyin | pH | 5.5-7.5 (300 unug/ml) | 5.5-7.5 (1g/300ml) |
Caddayn xalka | Nadiifi (2mg/ml) | ———— | |
Baruur | ≤ 5.0mg/g | ≤ 1.0mg/g | |
Kininase | ———— | R Qiimaha: ≥ 0.8 | |
Maado u eg Trypsin | ———— | Qiimaha T: ≤ 0.05 | |
Protease | A280≤ 0.2 | A280≤ 0.2 | |
Luminta qalajinta | ≤ 5.0% (60℃ Vacuum ku qallalan, 4 saac) | ≤ 2.0% (60℃ Vacuum ku qallalan, 4 saac) | |
Hadhaaga dabka | ≤ 3.0% | ≤ 3.0% | |
Kinin-sii daynta hawsha | ———— | ≥ 500ng bradykinin u dhiganta/min/cutubkiiba | |
daahirnimo | ≥ 75% (afka ah) | ———— | |
≥ 90% (durida) | |||
Bakteeriyada endotoxin | ≤ 2.5 EU/cutub (ku duritaan) | ———— | |
Qiimayn | Dhaqdhaqaaqa enzyme | ———— | ≥ 25 halbeeg/mg |
Dhaqdhaqaaq gaar ah | ≥ 300 unug/mg borotiin (oo afka ah) | ≥ 100 unug/mg borotiin | |
≥ 600 unug/mg borotiin (ku duritaan) | |||
Waxyeellada Microbial | TAMC | ≤ 1000cfu/g (afka ah) | ≤ 1000cfu/g |
≤ 100cfu/g (duritaan) | |||
TYMC | ≤ 100cfu/g | ≤ 100cfu/g | |
E.coli | waafaqsan | waafaqsan | |
Salmonella | waafaqsan | waafaqsan |
Waxaan dooneynaa inaan nafteena u hurno si aan u siino iibsadayaashayada sharafta leh oo ay la socdaan alaabada iyo adeegyada ugu xiisaha badan ee loogu talagalay Naqshad Cusub oo Fashion ah ee Shiinaha Tayada Sare ee Kallikrein CAS 9001-01-8 Pancreatic Kininogenase Kallikrein Powder, Marna ma joojineyno hagaajinta farsamada iyo tayada si aan u sii wadno la soco isbeddellada horumarineed ee warshadahan oo si fiican ula kulanto qanacsanaantaada.Haddii aad xiisaynayso alaabtayada, fadlan nala soo xiriir si xor ah.
Naqshad Cusub oo Fashion ahShiinaha Kininogenase Kallikrein, Kallikrein, Khibradayadu waxay naga dhigaysaa mid muhiim u ah indhaha macaamiishayada.Tayadayadu waxay lafteeda u hadashaa guryaha sida inayan isku dhejin, daadin ama jabin, sidaa darteed macaamiishayadu waxay had iyo jeer ku kalsoonaan doonaan markay dalbanayaan dalabka.